1-chloro-2-[2-(2-methoxy-4-methylphenoxy)ethoxy]-4-methylbenzene profile

ID Source	ID
PubMed CID	2289107
CHEMBL ID	1427154
CHEBI ID	116390

ID Source

PubMed CID

2289107

CHEMBL ID

1427154

CHEBI ID

116390

Synonym
smr000195240
MLS000572933 ,
1-chloro-2-[2-(2-methoxy-4-methylphenoxy)ethoxy]-4-methylbenzene
CHEBI:116390
HMS2305H09
CHEMBL1427154
Q27199274

Synonym

smr000195240

MLS000572933 ,

1-chloro-2-[2-(2-methoxy-4-methylphenoxy)ethoxy]-4-methylbenzene

CHEBI:116390

HMS2305H09

CHEMBL1427154

Q27199274

Drug Classes (1)

Class	Description
methoxybenzenes	Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class

Description

methoxybenzenes

Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups.

[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (23)

Potency Measurements

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Chain A, Beta-lactamase	Escherichia coli K-12	Potency	44.6684	0.0447	17.8581	100.0000	AID485341
Chain A, Cruzipain	Trypanosoma cruzi	Potency	19.9526	0.0020	14.6779	39.8107	AID1476
Luciferase	Photinus pyralis (common eastern firefly)	Potency	13.4591	0.0072	15.7588	89.3584	AID588342
glp-1 receptor, partial	Homo sapiens (human)	Potency	14.1254	0.0184	6.8060	14.1254	AID624417
TDP1 protein	Homo sapiens (human)	Potency	24.5192	0.0008	11.3822	44.6684	AID686978; AID686979
Microtubule-associated protein tau	Homo sapiens (human)	Potency	14.1254	0.1800	13.5574	39.8107	AID1460
apical membrane antigen 1, AMA1	Plasmodium falciparum 3D7	Potency	39.8107	0.7079	12.1943	39.8107	AID720542
aldehyde dehydrogenase 1 family, member A1	Homo sapiens (human)	Potency	39.8107	0.0112	12.4002	100.0000	AID1030
nonstructural protein 1	Influenza A virus (A/WSN/1933(H1N1))	Potency	4.4668	0.2818	9.7212	35.4813	AID2326
bromodomain adjacent to zinc finger domain 2B	Homo sapiens (human)	Potency	31.6228	0.7079	36.9043	89.1251	AID504333
euchromatic histone-lysine N-methyltransferase 2	Homo sapiens (human)	Potency	1.9953	0.0355	20.9770	89.1251	AID504332
polyunsaturated fatty acid lipoxygenase ALOX12	Homo sapiens (human)	Potency	6.3096	1.0000	12.2326	31.6228	AID1452
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	Homo sapiens (human)	Potency	2.2387	0.0018	15.6638	39.8107	AID894
DNA polymerase beta	Homo sapiens (human)	Potency	12.5893	0.0224	21.0102	89.1251	AID485314
mitogen-activated protein kinase 1	Homo sapiens (human)	Potency	6.3096	0.0398	16.7842	39.8107	AID1454
ubiquitin carboxyl-terminal hydrolase 2 isoform a	Homo sapiens (human)	Potency	11.2202	0.6561	9.4520	25.1189	AID463254
serine/threonine-protein kinase PLK1	Homo sapiens (human)	Potency	23.7781	0.1683	16.4040	67.0158	AID720504
lethal(3)malignant brain tumor-like protein 1 isoform I	Homo sapiens (human)	Potency	39.8107	0.0752	15.2253	39.8107	AID485360
histone acetyltransferase KAT2A isoform 1	Homo sapiens (human)	Potency	39.8107	0.2512	15.8432	39.8107	AID504327
neuropeptide S receptor isoform A	Homo sapiens (human)	Potency	10.0000	0.0158	12.3113	615.5000	AID1461
Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)	Potency	15.8489	0.3162	12.7657	31.6228	AID881
Histamine H2 receptor	Cavia porcellus (domestic guinea pig)	Potency	15.8489	0.0063	8.2350	39.8107	AID881
TAR DNA-binding protein 43	Homo sapiens (human)	Potency	31.6228	1.7783	16.2081	35.4813	AID652104
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (39)

Process	via Protein(s)	Taxonomy
lipid metabolic process	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
phospholipid metabolic process	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
apoptotic process	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
negative regulation of cell population proliferation	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
positive regulation of macrophage derived foam cell differentiation	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
arachidonic acid metabolic process	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
negative regulation of cell migration	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
prostate gland development	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
regulation of epithelial cell differentiation	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
positive regulation of chemokine production	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
positive regulation of peroxisome proliferator activated receptor signaling pathway	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
positive regulation of keratinocyte differentiation	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
negative regulation of cell cycle	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
negative regulation of growth	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
hepoxilin biosynthetic process	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
endocannabinoid signaling pathway	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
cannabinoid biosynthetic process	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
lipoxin A4 biosynthetic process	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
linoleic acid metabolic process	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
lipid oxidation	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
lipoxygenase pathway	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
negative regulation of protein phosphorylation	TAR DNA-binding protein 43	Homo sapiens (human)
mRNA processing	TAR DNA-binding protein 43	Homo sapiens (human)
RNA splicing	TAR DNA-binding protein 43	Homo sapiens (human)
negative regulation of gene expression	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of protein stability	TAR DNA-binding protein 43	Homo sapiens (human)
positive regulation of insulin secretion	TAR DNA-binding protein 43	Homo sapiens (human)
response to endoplasmic reticulum stress	TAR DNA-binding protein 43	Homo sapiens (human)
positive regulation of protein import into nucleus	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of circadian rhythm	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of apoptotic process	TAR DNA-binding protein 43	Homo sapiens (human)
negative regulation by host of viral transcription	TAR DNA-binding protein 43	Homo sapiens (human)
rhythmic process	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of cell cycle	TAR DNA-binding protein 43	Homo sapiens (human)
3'-UTR-mediated mRNA destabilization	TAR DNA-binding protein 43	Homo sapiens (human)
3'-UTR-mediated mRNA stabilization	TAR DNA-binding protein 43	Homo sapiens (human)
nuclear inner membrane organization	TAR DNA-binding protein 43	Homo sapiens (human)
amyloid fibril formation	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of gene expression	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (16)

Process	via Protein(s)	Taxonomy
iron ion binding	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
calcium ion binding	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
protein binding	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
lipid binding	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
linoleate 13S-lipoxygenase activity	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
arachidonate 8(S)-lipoxygenase activity	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
arachidonate 15-lipoxygenase activity	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
linoleate 9S-lipoxygenase activity	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
double-stranded DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
RNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
mRNA 3'-UTR binding	TAR DNA-binding protein 43	Homo sapiens (human)
protein binding	TAR DNA-binding protein 43	Homo sapiens (human)
lipid binding	TAR DNA-binding protein 43	Homo sapiens (human)
identical protein binding	TAR DNA-binding protein 43	Homo sapiens (human)
pre-mRNA intronic binding	TAR DNA-binding protein 43	Homo sapiens (human)
molecular condensate scaffold activity	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (16)

Process	via Protein(s)	Taxonomy
nucleus	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
cytosol	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
cytoskeleton	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
plasma membrane	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
adherens junction	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
focal adhesion	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
membrane	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
extracellular exosome	Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)
intracellular non-membrane-bounded organelle	TAR DNA-binding protein 43	Homo sapiens (human)
nucleus	TAR DNA-binding protein 43	Homo sapiens (human)
nucleoplasm	TAR DNA-binding protein 43	Homo sapiens (human)
perichromatin fibrils	TAR DNA-binding protein 43	Homo sapiens (human)
mitochondrion	TAR DNA-binding protein 43	Homo sapiens (human)
cytoplasmic stress granule	TAR DNA-binding protein 43	Homo sapiens (human)
nuclear speck	TAR DNA-binding protein 43	Homo sapiens (human)
interchromatin granule	TAR DNA-binding protein 43	Homo sapiens (human)
nucleoplasm	TAR DNA-binding protein 43	Homo sapiens (human)
chromatin	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (13)

Assay ID	Title	Year	Journal	Article
AID504812	Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810	Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635	Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	3 (60.00)	24.3611
2020's	1 (20.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe

Studies, This Drug (%)

All Drugs %

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (20.00)

29.6817

2010's

3 (60.00)

24.3611

2020's

1 (20.00)

2.80

[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type

This drug (%)

All Drugs (%)

Trials

0 (0.00%)

5.53%

Reviews

0 (0.00%)

6.00%

Case Studies

0 (0.00%)

4.05%

Observational

0 (0.00%)

0.25%

Other

5 (100.00%)

84.16%

[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Classes	Roles
tyrphostin a1	[no description available]	low	methoxybenzenes	geroprotector
anethole trithione	[no description available]	low	methoxybenzenes
capsaicin	[no description available]	low	methoxybenzenes; phenols
dilazep	[no description available]	low	benzoate ester; diazepane; diester; methoxybenzenes	cardioprotective agent; platelet aggregation inhibitor; vasodilator agent
guaifenesin	[no description available]	low	methoxybenzenes
mefexamide	[no description available]	low	methoxybenzenes
mescaline	[no description available]	low	methoxybenzenes; phenethylamine alkaloid; primary amino compound	hallucinogen
mofezolac	[no description available]	low	methoxybenzenes
4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone	[no description available]	low	methoxybenzenes
thonzylamine	[no description available]	low	methoxybenzenes
trimethoprim	[no description available]	low	aminopyrimidine; methoxybenzenes	antibacterial drug; diuretic; drug allergen; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; environmental contaminant; xenobiotic
thonzylamine monohydrochloride	[no description available]	low	methoxybenzenes
mephenoxalone	[no description available]	low	methoxybenzenes
N-(2-methoxyphenyl)acetamide	[no description available]	low	acetamides; methoxybenzenes
creosol	[no description available]	low	methoxybenzenes; phenols
2-methyl-4-methoxyaniline	[no description available]	low	methoxybenzenes
4-methyl anisole	[no description available]	low	methoxybenzenes
4-anisidine	[no description available]	low	methoxybenzenes; primary amino compound; substituted aniline	genotoxin; reagent
3,4,5-trimethoxybenzoic acid	[no description available]	low	benzoic acids; methoxybenzenes	human urinary metabolite; human xenobiotic metabolite; plant metabolite
cresidine	[no description available]	low	methoxybenzenes
mequinol	[no description available]	low	methoxybenzenes; phenols	metabolite
1,3-dimethoxybenzene	[no description available]	low	methoxybenzenes
ethamivan	[no description available]	low	methoxybenzenes; phenols
topanol 354	[no description available]	low	methoxybenzenes; phenols
phloroglucinol dimethyl ether	[no description available]	low	methoxybenzenes; phenols
methoxyhydroxyphenylglycol	[no description available]	low	methoxybenzenes; phenols
paeonol	[no description available]	low	methoxybenzenes; phenols	metabolite
guaiacol carbonate	[no description available]	low	methoxybenzenes
4-methoxy-3-phenylenediamine	[no description available]	low	methoxybenzenes
1,2,3-trimethoxybenzene	[no description available]	low	methoxybenzenes	plant metabolite
propanidid	[no description available]	low	methoxybenzenes
3-methoxy-4-hydroxyphenylethanol	[no description available]	low	methoxybenzenes; phenols
dimethophrine	[no description available]	low	methoxybenzenes; phenols
4-vinyl-2,6-dimethoxyphenol	[no description available]	low	methoxybenzenes; phenols
arildone	[no description available]	low	methoxybenzenes
meobentine	[no description available]	low	methoxybenzenes
4-(4-Methoxyphenyl)-2-butanone	[no description available]	low	methoxybenzenes
4-ethylguaiacol	[no description available]	low	methoxybenzenes; phenols
trithiozine	[no description available]	low	methoxybenzenes
1,2,4-trimethoxybenzene	[no description available]	low	methoxybenzenes
g 29505	[no description available]	low	methoxybenzenes
brodimoprim	[no description available]	low	aminopyrimidine; bromobenzenes; methoxybenzenes	antibacterial drug; antiinfective agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor
1,3,5-trimethoxybenzene	[no description available]	low	methoxybenzenes	biomarker; human xenobiotic metabolite
2-hydroxy-4-methoxybenzaldehyde	[no description available]	low	methoxybenzenes; phenols
4-iodoanisole	[no description available]	low	methoxybenzenes
moprolol	[no description available]	low	methoxybenzenes
vanitiolide	[no description available]	low	methoxybenzenes; phenols
2,5-di-tert-butyl-4-hydroxyanisole	[no description available]	low	methoxybenzenes; phenols
3,5-dimethoxytoluene	[no description available]	low	methoxybenzenes; toluenes	fragrance; plant metabolite
zinniol	[no description available]	low	methoxybenzenes
sr 95531	[no description available]	low	methoxybenzenes
2-o-methylpyrogallol	[no description available]	low	methoxybenzenes; phenols
cilomilast	[no description available]	low	methoxybenzenes
4'-demethyldesoxypodophyllotoxin	[no description available]	low	furonaphthodioxole; gamma-lactone; lignan; methoxybenzenes; phenols	antineoplastic agent; antioxidant; immunosuppressive agent; plant metabolite
myricanone	[no description available]	low	aromatic ether; cyclic ketone; diarylheptanoid; methoxybenzenes; phenols	antineoplastic agent; plant metabolite
nordihydrocapsaicin	[no description available]	low	methoxybenzenes; phenols
isomhpg	[no description available]	low	methoxybenzenes; phenols
n-demethyltramadol	[no description available]	low	methoxybenzenes
5-(3,4,5-trimethoxyphenyl)-3H-1,3,4-oxadiazol-2-one	[no description available]	low	methoxybenzenes
anthricin	[no description available]	low	furonaphthodioxole; gamma-lactone; lignan; methoxybenzenes	antineoplastic agent; apoptosis inducer; plant metabolite
7-(4-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidine	[no description available]	low	methoxybenzenes
knipholone	[no description available]	low	aromatic ketone; dihydroxyanthraquinone; methoxybenzenes; methyl ketone; polyphenol; resorcinols	antineoplastic agent; antioxidant; antiplasmodial drug; leukotriene antagonist; metabolite
yatein	[no description available]	low	benzodioxoles; butan-4-olide; lignan; methoxybenzenes	plant metabolite
8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pent-4-yn-1-yl-9H-purin-6-amine	[no description available]	low	6-aminopurines; acetylenic compound; methoxybenzenes; monochlorobenzenes; organofluorine compound	antineoplastic agent; Hsp90 inhibitor
chavibetol	[no description available]	low	methoxybenzenes; phenols
6-amino-4-(2-methoxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile	[no description available]	low	methoxybenzenes; pyranopyrazole
6-amino-4-[4-(2-amino-2-oxoethoxy)-2-chloro-5-methoxyphenyl]-5-cyano-2-methyl-4H-pyran-3-carboxylic acid methyl ester	[no description available]	low	methoxybenzenes
N-butyl-N-[5-(3,4,5-trimethoxyphenyl)-1,3,4-thiadiazol-2-yl]-2-furancarboxamide	[no description available]	low	methoxybenzenes
2-(ethylthio)-5-(4-methoxyphenyl)-1,3,4-oxadiazole	[no description available]	low	methoxybenzenes
6-amino-3-(methoxymethyl)-4-(4-methoxyphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile	[no description available]	low	methoxybenzenes; pyranopyrazole
5-(4-methoxyphenyl)-7-(4-methylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine	[no description available]	low	methoxybenzenes
5-(4-bromophenyl)-4-(4-hydroxy-3-methoxyphenyl)-3-methyl-2,4-dihydropyrrolo[3,4-c]pyrazol-6-one	[no description available]	low	methoxybenzenes; phenols
3-(2-furanylmethyl)-8-(4-methoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile	[no description available]	low	methoxybenzenes
2-methoxy-6-[[(1-propyl-5-benzimidazolyl)amino]methyl]phenol	[no description available]	low	methoxybenzenes; phenols
1-(4-Methoxyphenyl)-2-nitroethylene	[no description available]	low	methoxybenzenes
5-(5-chloro-2-methoxyphenyl)-3H-1,3,4-oxadiazole-2-thione	[no description available]	low	methoxybenzenes
brd32048	[no description available]	low	methoxybenzenes; substituted aniline
2-methoxy-6-[[(1-methyl-2-benzimidazolyl)amino]methyl]phenol	[no description available]	low	methoxybenzenes; phenols
4-chloro-N-(3,4,5-trimethoxyphenyl)-5-dithiazolimine	[no description available]	low	methoxybenzenes; substituted aniline
(1E,4E)-1,5-bis(4-methoxyphenyl)penta-1,4-dien-3-one	[no description available]	low	methoxybenzenes
5-amino-3-(4-methoxyphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester	[no description available]	low	methoxybenzenes; substituted aniline
(4-methoxyphenyl)-(4-methyl-1-piperazinyl)methanethione	[no description available]	low	methoxybenzenes
(3-bromo-4-methoxyphenyl)-(4-methyl-1-piperazinyl)methanethione	[no description available]	low	methoxybenzenes
2-propyl-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole	[no description available]	low	methoxybenzenes
1-azepanyl-(4-methoxyphenyl)methanethione	[no description available]	low	methoxybenzenes
1-[[(1,5-dimethyl-3-pyrazolyl)-oxomethyl]amino]-3-(2-methoxyphenyl)thiourea	[no description available]	low	methoxybenzenes; substituted aniline
1-(4-methoxyphenyl)-3-[[oxo(thiophen-2-yl)methyl]amino]thiourea	[no description available]	low	methoxybenzenes; substituted aniline
N2,N4-bis(4-methoxyphenyl)pyrimidine-2,4-diamine	[no description available]	low	methoxybenzenes; substituted aniline
2-(4-methoxyphenyl)-5-(3-pyridinyl)-1,3,4-oxadiazole	[no description available]	low	methoxybenzenes
2-(2-methoxyphenoxy)-N-[(2-methoxyphenyl)methyl]acetamide	[no description available]	low	methoxybenzenes
N4-(4-methoxyphenyl)-1,3,5-triazaspiro[5.5]undeca-1,4-diene-2,4-diamine	[no description available]	low	methoxybenzenes; substituted aniline
4-mercapto-5-(4-methoxyphenyl)-2-oxo-1,5-diazaspiro[5.5]undec-3-ene-3-carbonitrile	[no description available]	low	methoxybenzenes; substituted aniline
4-[2-(3-methoxyanilino)-4-thiazolyl]phenol	[no description available]	low	methoxybenzenes; substituted aniline
N-(3-chloro-4-methoxyphenyl)-4,6-dimethoxy-1,3,5-triazin-2-amine	[no description available]	low	methoxybenzenes; substituted aniline
N-[3-cyano-4-(4-methoxyphenyl)-5-methyl-2-thiophenyl]-2-methyl-3-pyrazolecarboxamide	[no description available]	low	methoxybenzenes
5-[(3,5-dimethyl-4-nitro-1-pyrazolyl)methyl]-N-[(4-methoxyphenyl)methyl]-2-furancarboxamide	[no description available]	low	methoxybenzenes
N-cyclohexyl-2-[[5-[(4-methoxyphenyl)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]acetamide	[no description available]	low	methoxybenzenes
2-[[5-[(4-methoxyphenyl)methyl]-1,3,4-oxadiazol-2-yl]thio]-N-(4-methyl-2-thiazolyl)acetamide	[no description available]	low	methoxybenzenes
6-[[(4,6-dimethyl-2-pyrimidinyl)thio]methyl]-N2-(4-methoxyphenyl)-1,3,5-triazine-2,4-diamine	[no description available]	low	methoxybenzenes; substituted aniline
3-(4-methoxyphenyl)-2-(4-methoxyphenyl)imino-4-thiazolidinone	[no description available]	low	methoxybenzenes; substituted aniline
N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]-5-methyl-3-isoxazolecarboxamide	[no description available]	low	methoxybenzenes
N-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]carbamic acid methyl ester	[no description available]	low	methoxybenzenes
3-(4-methoxyphenyl)-2,4-dihydrothiazolo[3,2-a][1,3,5]triazin-6-one	[no description available]	low	methoxybenzenes; substituted aniline
N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide	[no description available]	low	methoxybenzenes
zucapsaicin	[no description available]	low	methoxybenzenes; phenols
N-[[[2-(2-methoxyphenoxy)-1-oxoethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamide	[no description available]	low	methoxybenzenes
1-(3-methoxyphenyl)-3-[[3-(4-nitro-1-pyrazolyl)-1-oxopropyl]amino]thiourea	[no description available]	low	methoxybenzenes; substituted aniline
N-(5-chloro-2-methoxyphenyl)-5-pyridin-4-yl-1,3,4-thiadiazol-2-amine	[no description available]	low	methoxybenzenes; substituted aniline
2-[(6-amino-3,5-dicyano-4-thiophen-2-yl-2-pyridinyl)thio]-N-[(2-methoxyphenyl)methyl]acetamide	[no description available]	low	methoxybenzenes
1-[[(4-bromo-2-methyl-3-pyrazolyl)-oxomethyl]amino]-3-(2-methoxy-5-methylphenyl)thiourea	[no description available]	low	methoxybenzenes; substituted aniline
1-[2-(2-chlorophenoxy)ethoxy]-2-methoxy-4-methylbenzene	[no description available]	low	methoxybenzenes
N-[2-(4-methoxyphenyl)ethyl]-2,3-dihydro-1,4-dioxin-5-carboxamide	[no description available]	low	methoxybenzenes
2-(4-methoxyphenyl)-5-(2-methylpropylthio)-1,3,4-oxadiazole	[no description available]	low	methoxybenzenes
1-[2-[[5-(2-methoxyanilino)-1,3,4-thiadiazol-2-yl]thio]-1-oxoethyl]-2-pyrrolidinone	[no description available]	low	methoxybenzenes; substituted aniline
4-(2-furanylmethyl)-3-[(3-methoxyphenyl)methyl]-1H-1,2,4-triazole-5-thione	[no description available]	low	methoxybenzenes
1-(3-methoxyphenyl)-3-(methyl-oxo-phenyl-$l^{6}-sulfanylidene)thiourea	[no description available]	low	methoxybenzenes; substituted aniline
2-amino-7-methyl-5-oxo-4-(2,3,4-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile	[no description available]	low	methoxybenzenes
2-amino-7-methyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile	[no description available]	low	methoxybenzenes
4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid (3-methylcyclohexyl) ester	[no description available]	low	methoxybenzenes; phenols
4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid (4-methoxyphenyl)methyl ester	[no description available]	low	methoxybenzenes; phenols
N'-[(4-methoxyphenyl)methyl]-N-phenylcarbamimidothioic acid (2,5-dioxo-3-pyrrolidinyl) ester	[no description available]	low	methoxybenzenes
1-ethoxy-3-(2-methoxy-4-prop-2-enylphenoxy)-2-propanol	[no description available]	low	methoxybenzenes
2-(1-adamantyl)-5-(4-ethoxy-3-methoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one	[no description available]	low	methoxybenzenes
2-(3,5-diphenyl-3,4-dihydropyrazol-2-yl)-2-(4-hydroxy-3-methoxyphenyl)acetonitrile	[no description available]	low	methoxybenzenes; phenols
5-(4-methoxyanilino)-2-[(3-methylphenoxy)methyl]-4-oxazolecarbonitrile	[no description available]	low	methoxybenzenes; substituted aniline
3-(4-methoxyphenyl)-N-methyl-5-(4-methylphenyl)-3,4-dihydropyrazole-2-carbothioamide	[no description available]	low	methoxybenzenes
1-[1-[2-(4-methoxyphenyl)ethyl]-2,5-dimethyl-3-pyrrolyl]-2-[(1-methyl-5-tetrazolyl)thio]ethanone	[no description available]	low	methoxybenzenes
7-(2-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidine	[no description available]	low	methoxybenzenes
2-(4-ethoxy-3-methoxyphenyl)-4-mercapto-3-(4-methoxyphenyl)-6-oxo-1,2-dihydropyrimidine-5-carbonitrile	[no description available]	low	methoxybenzenes; substituted aniline
2-[[3-(4-methoxyphenyl)-1,2,4-thiadiazol-5-yl]thio]acetic acid ethyl ester	[no description available]	low	methoxybenzenes
3-(4-methoxyphenyl)-N-[(4-methoxyphenyl)methyl]-4,5-dihydroisoxazole-5-carboxamide	[no description available]	low	methoxybenzenes
N-cyclohexyl-3-(3-methoxyphenyl)-4,5-dihydroisoxazole-5-carboxamide	[no description available]	low	methoxybenzenes
N-(2-methoxyethyl)-5-(3-methoxyphenyl)-3-isoxazolecarboxamide	[no description available]	low	methoxybenzenes
3-(4-methoxyphenyl)-3-(1-pyrrolyl)-N-(2-thiazolyl)propanamide	[no description available]	low	methoxybenzenes
5-(4-methoxyphenyl)-N-propan-2-yl-3-isoxazolecarboxamide	[no description available]	low	methoxybenzenes
N-(2-furanylmethyl)-5-(3-methoxyphenyl)-3-isoxazolecarboxamide	[no description available]	low	methoxybenzenes
3-(3-methoxyphenyl)-N-(3-pyridinyl)-4,5-dihydroisoxazole-5-carboxamide	[no description available]	low	methoxybenzenes
2-amino-6-ethyl-4-(4-methoxyphenyl)-8-[(4-methoxyphenyl)methyl]-4,5-dihydropyrano[3,2-c]pyridine-3-carbonitrile	[no description available]	low	methoxybenzenes
2-(2-methoxyphenyl)-1-methyl-3,5-dinitro-2H-pyridine	[no description available]	low	methoxybenzenes
N4-(2-furanylmethyl)-N2-(3-methoxyphenyl)-5-nitropyrimidine-2,4,6-triamine	[no description available]	low	methoxybenzenes; substituted aniline
4-[(4-ethoxy-3-methoxyphenyl)-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one	[no description available]	low	methoxybenzenes
2-[4-(4-methoxyphenyl)-2-thiazolyl]guanidine	[no description available]	low	methoxybenzenes
1-(Chloroacetyl)-5-[4-(difluoromethoxy)-3-methoxyphenyl]-3-thien-2-yl-4,5-dihydro-1H-pyrazole	[no description available]	low	methoxybenzenes	anticoronaviral agent
N-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)thio]acetamide	[no description available]	low	methoxybenzenes
3-hydroxy-6-(hydroxymethyl)-2-[(3-methoxyphenyl)-(2-pyridinylamino)methyl]-4-pyranone	[no description available]	low	methoxybenzenes
1-[[2-(2,4-dichlorophenoxy)-1-oxoethyl]amino]-3-(4-methoxyphenyl)thiourea	[no description available]	low	methoxybenzenes; substituted aniline
2-[[6-amino-2-(4-methoxyanilino)-5-nitro-4-pyrimidinyl]amino]ethanol	[no description available]	low	methoxybenzenes; substituted aniline
1-amino-3-(4-chloro-2-methoxy-5-methylphenyl)thiourea	[no description available]	low	methoxybenzenes; substituted aniline
2-[[2-(4-ethoxy-3-methoxyphenyl)-4-thiazolyl]methylthio]-5-methyl-1,3,4-thiadiazole	[no description available]	low	methoxybenzenes
6-(4-methoxyphenyl)-8-methyl-4-oxo-6H-pyrimido[2,1-b][1,3]thiazine-2,7-dicarboxylic acid O7-ethyl ester O2-methyl ester	[no description available]	low	methoxybenzenes
1-[2,5-dimethyl-1-(2-oxolanylmethyl)-3-pyrrolyl]-2-[[5-(4-methoxyanilino)-1,3,4-thiadiazol-2-yl]thio]ethanone	[no description available]	low	methoxybenzenes; substituted aniline
6-iodonordihydrocapsaicin	[no description available]	low	methoxybenzenes; phenols
pterostilbene	[no description available]	low	diether; methoxybenzenes; stilbenol	anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; hypoglycemic agent; neuroprotective agent; neurotransmitter; plant metabolite; radical scavenger
4-[5-(4-methoxyphenyl)-3-isoxazolyl]-N-(2-pyridinylmethyl)butanamide	[no description available]	low	methoxybenzenes
olvanil	[no description available]	low	methoxybenzenes; phenols
arvanil	[no description available]	low	methoxybenzenes; phenols
1-[2-(4-methoxyphenyl)ethyl]-3,5-dimethyl-4-nitropyrazole	[no description available]	low	methoxybenzenes
mdl 105725	[no description available]	low	methoxybenzenes; phenols
n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride	[no description available]	low	aromatic ether; hydrochloride; methoxybenzenes; tertiary amino compound	antipsychotic agent; receptor modulator
6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one	[no description available]	low	methoxybenzenes; substituted aniline
cardiogenol c	[no description available]	low	methoxybenzenes; substituted aniline
3-amino-2-cyano-5-(3-methoxyphenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid methyl ester	[no description available]	low	methoxybenzenes
N-[5-[2-(2-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-2-methylpentanamide	[no description available]	low	methoxybenzenes; substituted aniline
N-[5-[2-(5-chloro-2-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]hexanamide	[no description available]	low	methoxybenzenes; substituted aniline
N-[5-[2-(3-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-3-methylbutanamide	[no description available]	low	methoxybenzenes; substituted aniline
N-[5-[2-(2-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]heptanamide	[no description available]	low	methoxybenzenes; substituted aniline
N-[5-[2-(2-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]pentanamide	[no description available]	low	methoxybenzenes; substituted aniline
N-[5-[2-(3-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]heptanamide	[no description available]	low	methoxybenzenes; substituted aniline
aegeline	[no description available]	low	methoxybenzenes
siphonazole	[no description available]	low	methoxybenzenes; phenols
N-[(2-methoxyphenyl)methyl]-4-[[[2-(4-methyl-1-piperidinyl)-3,4-dioxo-1-cyclobutenyl]amino]methyl]-1-cyclohexanecarboxamide	[no description available]	low	methoxybenzenes
antrocamphin a	[no description available]	low	methoxybenzenes	anti-inflammatory agent; metabolite
3-(1,3-benzodioxol-5-yl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-(3-methyl-1-piperidinyl)-1-propanone	[no description available]	low	methoxybenzenes; phenols
2-[[4-(5-chloro-2-methoxyanilino)-6-(1-piperidinyl)-1,3,5-triazin-2-yl]amino]ethanol	[no description available]	low	methoxybenzenes; substituted aniline
2-[[4-(2-methoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol	[no description available]	low	methoxybenzenes; substituted aniline
2-[[4-(3-methoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol	[no description available]	low	methoxybenzenes; substituted aniline
2-[[4-(4-methoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanol	[no description available]	low	methoxybenzenes; substituted aniline
n-trans-feruloyloctopamine	[no description available]	low	methoxybenzenes; phenols
4-[[4-(2-methoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]-1-butanol	[no description available]	low	methoxybenzenes; substituted aniline
[(1R,5S)-6-azabicyclo[3.2.1]octan-6-yl]-[5-[(4-chloro-2-methoxyphenoxy)methyl]-3-isoxazolyl]methanone	[no description available]	low	methoxybenzenes
5-[(2-chloro-4-methoxyphenoxy)methyl]-N-[(6-methyl-2-pyridinyl)methyl]-3-isoxazolecarboxamide	[no description available]	low	methoxybenzenes
1-(3-methoxyphenyl)-2-[4-oxo-6-(trifluoromethyl)-1H-pyrimidin-2-yl]guanidine	[no description available]	low	methoxybenzenes; substituted aniline
2-[(4-methoxyphenyl)methylthio]-6-methyl-1H-pyrimidin-4-one	[no description available]	low	methoxybenzenes
bemotrizinol	[no description available]	low	methoxybenzenes

Condition	Indicated	Relationship Strength	Studies	Trials
Inflammation	0	low	1	0
Innate Inflammatory Response	0	low	1	0

1-chloro-2-[2-(2-methoxy-4-methylphenoxy)ethoxy]-4-methylbenzene

Cross-References

Synonyms (7)

Drug Classes (1)

Protein Targets (23)

Potency Measurements

Biological Processes (39)

Molecular Functions (16)

Ceullar Components (16)

Bioassays (13)

Research

Studies (5)

Study Types

1-chloro-2-[2-(2-methoxy-4-methylphenoxy)ethoxy]-4-methylbenzene

Cross-References

Synonyms (7)

Drug Classes (1)

Protein Targets (23)

Potency Measurements

Biological Processes (39)

Molecular Functions (16)

Ceullar Components (16)

Bioassays (13)

Research

Studies (5)

Study Types

Related Drugs (184)

Related Conditions (2)